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Diabetes Mellitus: A Fundamental and Clinical Text |
| © 2004 Lippincott Williams & Wilkins |
1 The Two Phases of Glucose-Stimulated Insulin Secretion Mechanisms and Controls
3 Processing of the Insulin Molecule
4 Electrophysiology of the Pancreatic β-Cell
5 Sulfonylurea Receptors, Adenosine triphosphate–Sensitive Potassium Channels, and Insulin Secretion
6 Insulinotropic Glucagon-Like Peptides
7 Detrimental Effects of Chronic Hyperglycemia on the Pancreatic β-Cell
8 Glucose Toxicity of the β-Cell Cellular and Molecular Mechanisms
11 Physiologic Action of Insulin
14 The Role of Insulin Receptor Substrate Proteins in Insulin Signaling and Metabolic Regulation
15 The Insulin Signaling Network and Insulin Action
16 Knockout Mice as a Tool to the Understanding of Diabetes Mellitus
17 Regulation of Insulin Action by Protein-Tyrosine Phosphatases
18 Small GTPAses and Serine/Threonine Protein Kinase Cascades in Insulin Signal Transduction
20 Regulation of Glycogen Synthesis
21 Insulin Action on Glucose Transport
22 Cellular and Molecular Processes Regulating Glucose Transporter 4 Translocation
23 Hormone-Sensitive Lipase, Perilipins, and the Control of Lipolysis in Adipocytes
24 Role for Phosphodiesterase 3B in Regulation of Lipolysis and Insulin Secretion
27 Insulin and the Ras-Dependent Signaling Pathway
28 Germline Manipulation of Glucose Transport and Glucose Homeostasis
29 Molecular Links Between Peroxisome Proliferator–Activated Receptor-γ and Metabolic Disease
30 Definition and Classification of Diabetes Mellitus and the Criteria for Diagnosis
31 The Natural History of Autoimmunity in Type 1A Diabetes Mellitus
32 Genetics of Type 1 Diabetes
33 Autoantibodies and the Disease Process of Type 1 Diabetes Mellitus
34 Roles of Cell-Mediated Immunity and Cytokines in the Pathogenesis of Type 1 Diabetes Mellitus
36 Associations Between Immune-Mediated (Type 1) Diabetes and Other Autoimmune Diseases
37 Role of Viruses in the Pathogenesis of Type 1 Diabetes Mellitus
38 Animal Models of Autoimmune Diabetes Mellitus
39 Insights from Transgenic and Gene Targeting Strategies in Type 1 Diabetes
40 Diabetic Ketoacidosis and the Hyperglycemic Hyperosmolar Syndrome
41 Application of the Diabetes Control and Complications Trial
42 Diet Therapy in Type 1 Diabetes Mellitus
43 Exercise for the Patient with Type 1 Diabetes Mellitus
44 Insulin Therapy and Home Monitoring for Type 1 Diabetes Mellitus
49 Gene Therapy for Metabolic Disease
50 Surrogate β-cells for Insulin Replacement Therapy
51 Stem Cells
52 Epidemiology of Type 2 Diabetes Mellitus
53 Metabolic Abnormalities in the Development of Type 2 Diabetes Mellitus
54 Noninvasive Imaging of Insulin Action and Resistance in Humans
57 Obesity in Type 2 Diabetes Mellitus
58 Effects of Aging on Glucose Homeostasis
59 Drug-Induced Diabetes Mellitus
60 Insulin Secretion in Type 2 Diabetes Mellitus
62 Glucose Transporters and Pathophysiologic States
63 Glucose Toxicity: Effect of Chronic Hyperglycemia on Insulin Action
64 Inflammation, Tumor Necrosis Factor-α, and Insulin Resistance
65 Adipokines: Regulators of Metabolic Integration and Energy Metabolism
66 Fatty Acids and Insulin Resistance
68 Candidate Genes for Type 2 Diabetes Mellitus
70 Maturity-Onset Diabetes of the Young: A Model for Genetic Studies of Diabetes Mellitus
71 Rodent Genetic Models of Obesity and Type 2 Diabetes Mellitus
73 Preventing Type 2 Diabetes: The Diabetes Prevention Program
74 Dietary Therapy in Type 2 Diabetes Mellitus: Spreading the Nutrient Load
75 Exercise in Patients with Type 2 Diabetes Mellitus
76 Insulin Secretagogues: Sulfonylureas, Meglitinides, and Phenylalanine Derivatives
77 Metformin
78 Peroxisome Proliferator-Activated Receptor Modulators
79 α-Glucosidase Inhibitors in the Treatment of Diabetes
80 Glinides
81 Combination Therapy in Type 2 Diabetes Mellitus
82 Intensive Insulin Therapy for Patients with Type 2 Diabetes
85 Intermediary Metabolism During Pregnancy: Implications for Diabetes Mellitus
86 Effects of Maternal Diabetes Mellitus on Intrauterine Development
87 Pregnancy and Complications of Diabetes Mellitus: Maternal and Fetal Implications
89 Pathophysiology of Diabetic Retinopathy
90 Pathogenesis of Diabetic Nephropathy
91 Diabetic Neuropathies: An Overview of Clinical Aspects, Pathogenesis, and Treatment
92 Diabetes Mellitus, Lipids, and Atherosclerosis
93 Pathophysiology of Hypertension in Diabetes
98 Biochemistry and Molecular Cell Biology of Diabetic Complications: A Unifying Mechanism
99 Hyperinsulinemia and Insulin Resistance
100 The Role of Growth Factors in the Pathogenesis of Diabetic Microvascular Complications
101 Oxidative Stress, Inflammation, and Diabetic Complications