Textbook of Gastroenterology
4th Edition

CHAPTER 105
ANATOMY, MICROSCOPIC STRUCTURE, AND CELL TYPES OF THE LIVER
Gary C. Kanel
The liver is a unique organ having a wide range of both structural and physiologic functions. Understanding the arrangements of all the individual components of the liver on both gross and light microscopic examination assisted by electron microscopic and immunoenzymatic features allows a better understanding of liver histopathology and pathophysiology. Study of the embryologic evolution of the hepatic and hepatobiliary elements also assists in understanding many of the key concepts in developmental abnormalities seen in a wide variety of both pediatric and adult liver diseases. This chapter outlines the gross and microscopic characteristics of the liver and briefly addresses liver function, with an introductory presentation of embryologic development.